Is Elastography Useful in Assessing Necrotizing Enterocolitis in Rats?

Background: Necrotizing enterocolitis (NEC) is among the most common and destructive diseases in neonatal period. Imaging methods are important early diagnosis treatment of such diseases. Ultrasound elastography (USE) a fast non-invasive imaging technique that deals with viscoelastic properties tissues. Objectives: The purpose this study to assess effectiveness USE, which determines tissue stiffness grayscale colored images, as an tool NEC. Materials Methods: Sixteen newborn Wistar albino gender rats were separated into two groups including eight each. first group (G-I) was taken control not exposed any intervention. second (G-II) 100% CO2 for 5 minutes 4°C 10 minutes. All these interventions applied twice per day 4 days. We observed elastographic data at 24, 48, 96 hours. sacrificed on fourth day. combination gray-scale US performed by 4-13 MHz average 12 bandwidth linear probe Esaote Ultrasonography Systems, MyLab60 model, produced Geneva, Italy; ElaXto application. Results: Statistically significant differences detected elastosonography ratios terminal ileum hours (P < 0.05). As ischemia period NEC prolonged, elastosonographic intestinum increased significantly. Conclusion: It found USE reliable superior features assessment age group. due its wide image window better gray scale color image. has been helpful diagnosis.